What do you mean? Can you post some more details and/or an example?
If you have a scene setup like this:
|-- Root_Node
|----- Child_Node
|-------- Child_Node_2
|----- Child_Node_3
Then you can use the properties/data like this:
get_node("Child_Node").data_here = "Foo"
get_node("Child_Node/Child_Node_2").other_data = "Bar"
var test = get_node("Child_Node_3").more_data