I think it has to be the same position relative to the scene's 0, 0 position, if you want it's origin centered you can put a centered control node and make it the "root" node of the 2d world so it's always centered even when you change the window size
ie I made this for a mobile game that needed to be centered but expandible,
GameHolder size is 0,0 and it's Layout is set to Centered
the 2d nodes are children of the GameHolder node

I hope it helps 👀